1 in 3 Ashkenazi Jews is a carrier of at least one Jewish genetic disease that may threaten infant health.
The American Congress of Obstetricians and Gynecologists (ACOG) recommends that individuals of Eastern European Jewish (Ashkenazi) ancestry be offered carrier screening for certain Jewish genetic diseases. Jewish genetic diseases are autosomal recessive disorders. When both parents are carriers of a specific genetic disease, there is a 1 in 4 (or 25%) chance with each pregnancy that they will have an affected child.
Screening results inform patients of their carrier status and can help guide decision-making for patients who are pregnant, planning a pregnancy, or considering fertility options.
Genetic carrier screening among Jewish and interfaith couples can be an important and empowering family planning tool for patients and their consulting physicians.